This strategic area aims to generate evidence that advances equitable access to high-quality health interventions, aligned with global commitments to Universal Health Coverage (UHC). It recognises that for interventions to achieve meaningful health impact, they must not only be clinically effective but also equitably delivered, of high quality, and efficiently utilised. Our research supports countries, particularly in sub-Saharan Africa, in designing and implementing health systems and policies that improve access, quality, equity, and efficiency.