KWTRP addresses three interconnected and rapidly evolving health threats – climate change, antimicrobial resistance (AMR), and non-communicable diseases (NCDs) – through an integrated, multidisciplinary framework linking environmental, biological, clinical, and health systems research. Our climate and health work examines how environmental change influences infectious disease transmission, and health system resilience. Our AMR research spans molecular, clinical, and health systems domains, investigating how resistance emerges and spreads, and identifying mitigation strategies across diagnostics, stewardship, and vaccines.

Our NCD portfolio addresses cardiovascular disease, mental health, and neurodevelopmental conditions, focusing on prevention, early detection, and management. This theme is inherently cross-cutting: climate change and AMR reshape the trajectory of infectious diseases; NCDs increasingly intersect with infectious conditions to create complex comorbidity profiles; and all three threats disproportionately affect vulnerable populations, placing growing pressure on already-strained health systems.