Clinical Research

Bio

Charles was born in Kenya, qualified in Cape Town, South Africa, with postgraduate training in Paediatrics in Manchester and London, United Kingdom. As a lecturer at University of Oxford, he returned to Kilifi Kenya in 1989, to help set up an unit to study severe malaria in African children. Thereafter he spent 2 years as a Post-doctoral fellow at Johns Hopkins, USA; studying mechanisms of brain damage in central nervous system infections. He completed his training in Paediatric Neurology at Great Ormond Street Hospital, UK. In 1998 he was awarded a Wellcome Trust Senior Clinical Fellowship at University College London, to return to Kilifi, to study CNS infections in children. He has published on a wide variety of subjects concerning sick children in tropical countries. In 2011 he took up a professorship in Psychiatry at the University of Oxford to concentrate of neurological and mental illness disorders in children living in Africa.

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Current Work

He conducts research on CNS infections in children; epidemiological studies of epilepsy and neurological impairment; tetanus, jaundice and sepsis in neonates. At present he is conducting studies of Autism and Epilepsy in Africa and working on sickle cell disease in Tanzania.

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Recent publications

Factor structure and item response of psychosis symptoms among Kenyan adults.
Jaguga, F., Ametaj, A., Kim, H. H., Stroud, R. E., Newton, C. R., Kariuki, S. M., Kwobah, E. K., Atwoli, L., Gelaye, B., Korte, K. J.
J Affect Disord, (2022). 317:136-141

Prevalence and factors associated with mild depressive and anxiety symptoms in older adults living with HIV from the Kenyan coast.
Mwangala, P. N., Nasambu, C., Wagner, R. G., Newton, C. R., Abubakar, A.
J Int AIDS Soc, (2022). 25 Suppl 4:e25977

Neurodevelopmental and growth outcomes after invasive Group B Streptococcus in early infancy: A multi-country matched cohort study in South Africa, Mozambique, India, Kenya, and Argentina.
Paul, P., Chandna, J., Procter, S. R., Dangor, Z., Leahy, S., Santhanam, S., John, H. B., Bassat, Q., Bramugy, J., Bardaji, A., Abubakar, A., Nasambu, C., Libster, R., Yanotti, C. S., Seedat, F., Horvath-Puho, E., Hossain, A. K. M. T., Sadeq-Ur Rahman, Q., Jit, M., Newton, C. R., Milner, K., Goncalves, B. P., Lawn, J. E., GBS long term outcomes LMIC collaborative group
EClinicalMedicine, (2022). 47:101358

What is next in African neuroscience?.
Donald, K. A., Maina, M., Patel, N., Nguemeni, C., Mohammed, W., Abubakar, A., Brown, M., Stoyanova, R., Welchman, A., Walker, N., Willett, A., Kariuki, S. M., Figaji, A., Stein, D. J., Ihunwo, A. O., Daniels, W., Newton, C. R.
Elife, (2022). 11:e80488

Sociocultural perspectives on suicidal behaviour at the Coast Region of Kenya: an exploratory qualitative study.
Ongeri, L., Nyawira, M., Kariuki, S. M., Theuri, C., Bitta, M., Penninx, B., Newton, C. R., Tijdink, J.
BMJ Open, (2022). 12:e056640