Epidemiology & Demography

Bio


I am a molecular epidemiologist interested in the epidemiology and evolutionary dynamics of respiratory and gastrointestinal viruses in low-income settings. I trained as a Biochemist (University of Nairobi), and later earned an MSc, then PhD, in Virus Molecular Epidemiology (Open University). In 2022, I was awarded a Wellcome Career Development Award to study rates, determinants and transmissibility of respiratory virus reinfections. Currently, I head the Pathogen Epidemiology and Omics (PEO) research group within the KEMRI-Wellcome Trust Research Programme. The PEO team  conducts field studies, wholesome/systems laboratory (diagnostics, genomic and immunologic) characterisation for a range of infectious agents and downstream bioinformatic, statistical and modelling studies to elucidate host-pathogen interactions, infectious agent dispersal and predict intervention impact. Previous research roles: 1)Co-lead COVID-19 diagnostics  and genomic surveillance at KEMRI-Wellcome Trust Research Programme, 2) A Mid-Career Research Fellow supported by the Initiative to Develop African Research Leaders (IDeAL) studying the genomics of viral diarrhoea in Kenya prior to and following the introduction of the rotavirus vaccine, 3) Postdoctoral Scientist/Lead Bioinformatician for the SPReD studies (Studying the Pathways of Respiratory Virus Diseases).

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Current Work


An investigation into the rates, determinants, and transmission of respiratory virus reinfections (ResViRe) funded through the Wellcome Career Development Award Discovery Scheme

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Research Groups


ResViRe Water sequencing Adenovirus sequencing and antigenic characterisation

Recent publications


Surveillance of respiratory viruses in the outpatient setting in rural coastal Kenya: baseline epidemiological observations.
Nyiro, J. U., Munywoki, P., Kamau, E., Agoti, C., Gichuki, A., Etyang, T., Otieno, G., Nokes, D. J.
Wellcome Open Res, (2018). 3:89

A27 Using whole genome sequence data and minority variant profiles to elucidate transmission patterns during RSV household outbreaks.
Githinji, G., Agoti, C., Munywoki, P., Bett, A., Kellam, P., Cotton, M., Nokes, D. J.
Virus Evol, (2017). 3: